The Reorientation of T-Cell Polarity and Inhibition of Immunological Synapse Formation by CD46 Involves Its Recruitment to Lipid Rafts

Many infectious agents utilize CD46 for infection of human cells, and therapeutic applications of CD46-binding viruses are now being explored. Besides mediating internalization to enable infection, binding to CD46 can directly alter immune function. In particular, ligation of CD46 by antibodies or b...

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Autors principals: Ludford-Menting, Mandy J., Crimeen-Irwin, Blessing, Oliaro, Jane, Pasam, Anupama, Williamson, David, Pedersen, Natalie, Guillaumot, Patricia, Christansen, Dale, Manie, Serge, Gaus, Katharina, Russell, Sarah M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067059/
https://ncbi.nlm.nih.gov/pubmed/21490803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/521863
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