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Human fibroblast growth factor 1 gene expression in vascular smooth muscle cells is modulated via an alternate promoter in response to serum and phorbol ester.

We have previously isolated the human FGF-1 gene in order to elucidate the molecular basis of its gene expression. The gene spans over 100 kbp and encodes multiple transcripts expressed in a tissue- and cell-specific manner. Two variants of FGF-1 mRNA (designated FGF-1.A and 1.B), which differ in th...

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Autors principals: Chotani, M A, Payson, R A, Winkles, J A, Chiu, I M
Format: Artigo
Idioma:Inglês
Publicat: 1995
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC306694/
https://ncbi.nlm.nih.gov/pubmed/7533902
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