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Epstein–Barr virus LMP2A imposes sensitivity to apoptosis

In cell lines, the Epstein–Barr virus (EBV)-encoded protein latent membrane protein 2A (LMP2A) protects B-cells from apoptosis by blocking B-cell receptor (BCR) signalling. However, EBV-infected B-cells in vivo are extremely different from cell lines. This study used a murine transgenic model in whi...

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Bibliografiske detaljer
Main Authors: Swanson-Mungerson, Michelle, Bultema, Rebecca, Longnecker, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066549/
https://ncbi.nlm.nih.gov/pubmed/20484564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.021444-0
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