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HMGB1 promotes MMP-9 upregulation through TLR4 after cerebral ischemia
BACKGROUND AND PURPOSE: HMGB1 is a nuclear protein and an alarmin that signals cell damage in response to injury. It is believed that following release from injured cells, HMGB1 binds to its receptors to stimulate cross-talk among cells and to drive components of the inflammatory cascade. This study...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066477/ https://ncbi.nlm.nih.gov/pubmed/20671243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.590463 |
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