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Solid Dispersions of Imidazolidinedione by PEG and PVP Polymers with Potential Antischistosomal Activities
Solid dispersions have been used as a strategy to improve the solubility, dissolution rate, and bioavailability of poor water-soluble drugs. The increase of the dissolution rate presented by (5Z)-3-(4-chloro-benzyl)-5-(4-nitro-benzylidene)-imidazolidine-2,4-dione (LPSF/FZ4) from the solid dispersion...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer US
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066376/ https://ncbi.nlm.nih.gov/pubmed/21360315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9556-z |
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