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Solid Dispersions of Imidazolidinedione by PEG and PVP Polymers with Potential Antischistosomal Activities

Solid dispersions have been used as a strategy to improve the solubility, dissolution rate, and bioavailability of poor water-soluble drugs. The increase of the dissolution rate presented by (5Z)-3-(4-chloro-benzyl)-5-(4-nitro-benzylidene)-imidazolidine-2,4-dione (LPSF/FZ4) from the solid dispersion...

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Bibliographische Detailangaben
Hauptverfasser: Guedes, Francimary L., de Oliveira, Boaz G., Hernandes, Marcelo Z., De Simone, Carlos A., Veiga, Francisco J. B., de Lima, Maria do Carmo A., Pitta, Ivan R., Galdino, Suely L., Neto, Pedro José Rolim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066376/
https://ncbi.nlm.nih.gov/pubmed/21360315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9556-z
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