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Development of Push–Pull Osmotic Tablets Using Chitosan–Poly(Acrylic Acid) Interpolymer Complex as an Osmopolymer

The objectives of this study were to prepare push–pull osmotic tablets (PPOT) of felodipine using an interpolymer complex of chitosan (CS) and poly(acrylic acid) (PAA) as an osmopolymer, and to study the mechanisms of drug release from these tablets. The interpolymer complexes were prepared with dif...

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Main Authors: Ketjinda, Wichan, Sinchaipanid, Nuttanan, Limsuwan, Pichet, Leuenberger, Hans, Mitrevej, Ampol
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066366/
https://ncbi.nlm.nih.gov/pubmed/21181509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9572-z
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