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Solution Formulation Development of a VEGF Inhibitor for Intravitreal Injection

PF-00337210 is a potent, selective small molecule inhibitor of VEGFRs and has been under consideration for the treatment of age-related macular degeneration. An ophthalmic solution formulation intended for intravitreal injection was developed. This formulation was designed to maximize drug propertie...

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Detalhes bibliográficos
Main Authors: Marra, Michelle T., Khamphavong, Penney, Wisniecki, Peter, Gukasyan, Hovhannes J., Sueda, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066352/
https://ncbi.nlm.nih.gov/pubmed/21312012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9591-4
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