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Evaluation of Ionotropic Cross-Linked Chitosan/Gelatin B Microspheres of Tramadol Hydrochloride

Microspheres of tramadol hydrochloride (TM) for oral delivery were prepared by complex coacervation method without the use of chemical cross-linking agents such as glutaraldehyde to avoid the toxic reactions and other undesirable effects of the chemical cross-linking agents. Alternatively, ionotropi...

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Detalhes bibliográficos
Main Authors: Basu, Sanat Kumar, Kavitha, Kunchu, Rupeshkumar, Mani
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066349/
https://ncbi.nlm.nih.gov/pubmed/21161459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9537-2
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