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Sex differences in the response to PARP-1 deletion and caspase inhibition after stroke
BACKGROUND AND PURPOSE: Emerging data suggests that the molecular cell death pathways triggered by ischemic insults differ in male and female brain. Cell death in males is initiated by poly (ADP-ribose) polymerase-1 (PARP-1) activation; however manipulation of this pathway paradoxically increases is...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066270/ https://ncbi.nlm.nih.gov/pubmed/21311064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.594861 |
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