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Molecular Architecture of the Human Mediator–RNA Polymerase II–TFIIF Assembly
The macromolecular assembly required to initiate transcription of protein-coding genes, known as the Pre-Initiation Complex (PIC), consists of multiple protein complexes and is approximately 3.5 MDa in size. At the heart of this assembly is the Mediator complex, which helps regulate PIC activity and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066130/ https://ncbi.nlm.nih.gov/pubmed/21468301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000603 |
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