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FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis During Aging

The progressive loss of muscle strength during aging is a common degenerative event of unclear pathogenesis. Although muscle functional decline precedes age-related changes in other tissues, its contribution to systemic aging is unknown. Here, we show that muscle aging is characterized in Drosophila...

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Detalhes bibliográficos
Main Authors: Demontis, Fabio, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066043/
https://ncbi.nlm.nih.gov/pubmed/21111239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.10.007
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