Glycogen synthase kinase-3β (GSK-3β) inhibitors AR-A014418 and B6B3O prevent human immunodeficiency virus–mediated neurotoxicity in primary human neurons

Glycogen synthase kinase-3β (GSK3β) role in human immunodeficiency virus (HIV)-associated neurodegeneration has been evidenced by previous investigations. In this study, we investigated the specificity of two GSK3β-specific inhibitors, AR-A014418 (A) and B6B30 (B) to prevent direct neurotoxicity in...

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Detalhes bibliográficos
Main Authors: Nguyen, Timothy B., Lucero, Ginger R., Chana, Gursharan, Hult, Britta J., Tatro, Erick T., Masliah, Eliezer, Grant, Igor, Achim, Cristian L., Everall, Ian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065998/
https://ncbi.nlm.nih.gov/pubmed/19688630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13550280903168131
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