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Evaluation of microsatellite variation in the 1000 Genomes Project pilot studies is indicative of the quality and utility of the raw data and alignments

We performed an analysis of global microsatellite variation on the two kindreds sequenced at high depth (~20×–60×) in the 1000 Genomes Project pilot studies because alterations in these highly mutable repetitive sequences have been linked with many phenotypes and disease risks. The standard alignmen...

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Detalhes bibliográficos
Main Authors: McIver, L. J., Fondon, J. W., Skinner, M. A., Garner, H. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065957/
https://ncbi.nlm.nih.gov/pubmed/21223998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2011.01.001
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