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Genetic Variation in the Presynaptic Norepinephrine Transporter is Associated with Blood Pressure Responses to Exercise in Healthy Humans

BACKGROUND: The presynaptic norepinephrine (NE) transporter (NET) mediates synaptic clearance and recycling of NE. NET-deficient transgenic mice have elevated blood pressure, heart rate, and catecholamine concentrations. However, the in vivo effects of common NET variants on cardiovascular regulatio...

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Detalhes bibliográficos
Main Authors: Kohli, Utkarsh, Hahn, Maureen K., English, Brett A., Sofowora, Gbenga G., Muszkat, Mordechai, Li, Chun, Blakely, Randy D., Stein, C. Michael, Kurnik, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065933/
https://ncbi.nlm.nih.gov/pubmed/21412203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328344f63e
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