Heme Oxygenase-1 Protects against Neutrophil-Mediated Intestinal Damage by Down-Regulation of Neutrophil p47(phox) and p67(phox) Activity and [Formula: see text] Production in a Two-Hit Model of Alcohol Intoxication and Burn Injury

Heme oxygenase-1 (HO-1) has been demonstrated to protect against tissue injury. Furthermore, HO-1 is also shown to be antioxidant. Our recent findings indicate that acute alcohol (EtOH) intoxication exacerbates postburn intestinal and lung tissue damage, and this was found to be neutrophil dependent...

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Bibliographic Details
Main Authors: Li, Xiaoling, Schwacha, Martin G., Chaudry, Irshad H., Choudhry, Mashkoor A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065786/
https://ncbi.nlm.nih.gov/pubmed/18453614
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