Characterization of Selective Ubiquitin and Ubiquitin-Like Protease Inhibitors Using a Fluorescence-Based Multiplex Assay Format

The reversible conjugation of ubiquitin and ubiquitin-like (UbL) proteins to protein substrates plays a critical role in the regulation of many cellular pathways. The removal of ubiquitin from target proteins is performed by ubiquitin proteases also known as deubiquitylases (DUBs). Owing to their su...

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Bibliografiske detaljer
Main Authors: Tian, Xufan, Isamiddinova, Nigora S., Peroutka, Raymond J., Goldenberg, Seth J., Mattern, Michael R., Nicholson, Benjamin, Leach, Craig
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2011
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065724/
https://ncbi.nlm.nih.gov/pubmed/21133675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0317
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