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Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm

In mature human sperm, genes of importance for embryo development (i.e., transcription factors) lack DNA methylation and bear nucleosomes with distinctive histone modifications, suggesting the specialized packaging of these developmental genes in the germline. Here, we explored the tractable zebrafi...

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Detalhes bibliográficos
Main Authors: Wu, Shan-Fu, Zhang, Haiying, Cairns, Bradley R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065705/
https://ncbi.nlm.nih.gov/pubmed/21383318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.113167.110
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