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RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression

Expression levels of many human genes are under the genetic control of expression quantitative trait loci (eQTLs). Despite technological advances, the precise molecular mechanisms underlying most eQTLs remain elusive. Here, we use deep mRNA sequencing of two CEU individuals to investigate those mech...

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Detalhes bibliográficos
Main Authors: Lalonde, Emilie, Ha, Kevin C.H., Wang, Zibo, Bemmo, Amandine, Kleinman, Claudia L., Kwan, Tony, Pastinen, Tomi, Majewski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065702/
https://ncbi.nlm.nih.gov/pubmed/21173033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.111211.110
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