Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors

Aberrant DNA methylation (DNAm) was first linked to cancer over 25 yr ago. Since then, many studies have associated hypermethylation of tumor suppressor genes and hypomethylation of oncogenes to the tumorigenic process. However, most of these studies have been limited to the analysis of promoters an...

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Main Authors: Feber, Andrew, Wilson, Gareth A., Zhang, Lu, Presneau, Nadege, Idowu, Bernadine, Down, Thomas A., Rakyan, Vardhman K., Noon, Luke A., Lloyd, Alison C., Stupka, Elia, Schiza, Vassia, Teschendorff, Andrew E., Schroth, Gary P., Flanagan, Adrienne, Beck, Stephan
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065699/
https://ncbi.nlm.nih.gov/pubmed/21324880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.109678.110
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