Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors

Aberrant DNA methylation (DNAm) was first linked to cancer over 25 yr ago. Since then, many studies have associated hypermethylation of tumor suppressor genes and hypomethylation of oncogenes to the tumorigenic process. However, most of these studies have been limited to the analysis of promoters an...

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Hauptverfasser: Feber, Andrew, Wilson, Gareth A., Zhang, Lu, Presneau, Nadege, Idowu, Bernadine, Down, Thomas A., Rakyan, Vardhman K., Noon, Luke A., Lloyd, Alison C., Stupka, Elia, Schiza, Vassia, Teschendorff, Andrew E., Schroth, Gary P., Flanagan, Adrienne, Beck, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065699/
https://ncbi.nlm.nih.gov/pubmed/21324880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.109678.110
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