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Sequence signatures of allosteric proteins towards rational design

Allostery is the phenomenon of changes in the structure and activity of proteins that appear as a consequence of ligand binding at sites other than the active site. Studying mechanistic basis of allostery leading to protein design with predetermined functional endpoints is an important unmet need of...

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Main Authors: Namboodiri, Saritha, Verma, Chandra, Dhar, Pawan K., Giuliani, Alessandro, Nair, Achuthsankar S.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065584/
https://ncbi.nlm.nih.gov/pubmed/22132054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11693-011-9072-9
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