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GEFH1 binds ASAP1 and regulates podosome formation

Invadopodia are cellular structures that are thought to mediate tumor invasion. ASAP1, an Arf GTPase-activating protein (GAP) containing a BAR domain, is a substrate of Src. ASAP1 is required for the assembly of invadopodia and podosomes, which are Src-induced structures related to invadopodia in NI...

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Bibliografiske detaljer
Main Authors: Shiba, Yoko, Randazzo, Paul A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065500/
https://ncbi.nlm.nih.gov/pubmed/21352810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.093
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