Divergent Protein Kinase A isoforms co-ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus

The genome of Aspergillus fumigatus encodes two isoforms of the catalytic subunit of the cAMP-dependent Protein Kinase (PKA). Although deletion of the class I isoform, pkaC1, leads to an attenuation of virulence, the function of the class II subunit, PkaC2, was previously uninvestigated. In this rep...

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Main Authors: Fuller, Kevin K., Richie, Daryl L., Feng, Xizhi, Krishnan, Karthik, Stephens, Timothy J., Wikenheiser-Brokamp, Kathryn A., Askew, David S., Rhodes, Judith C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065306/
https://ncbi.nlm.nih.gov/pubmed/21210869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07509.x
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