Exon-array profiling unlocks clinically and biologically relevant gene signatures from formalin-fixed paraffin-embedded tumour samples

BACKGROUND: Degradation and chemical modification of RNA in formalin-fixed paraffin-embedded (FFPE) samples hamper their use in expression profiling studies. This study aimed to show that useful information can be obtained by Exon-array profiling archival FFPE tumour samples. METHODS: Nineteen cervi...

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Bibliografiske detaljer
Main Authors: Hall, J S, Leong, H S, Armenoult, L S C, Newton, G E, Valentine, H R, Irlam, J J, Möller-Levet, C, Sikand, K A, Pepper, S D, Miller, C J, West, C M L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065290/
https://ncbi.nlm.nih.gov/pubmed/21407225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.66
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