Morphological predictors of BRCA1 germline mutations in young women with breast cancer

BACKGROUND: Knowing a young woman with newly diagnosed breast cancer has a germline BRCA1 mutation informs her clinical management and that of her relatives. We sought an optimal strategy for identifying carriers using family history, breast cancer morphology and hormone receptor status data. METHOD...

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Main Authors: Southey, M C, Ramus, S J, Dowty, J G, Smith, L D, Tesoriero, A A, Wong, E E M, Dite, G S, Jenkins, M A, Byrnes, G B, Winship, I, Phillips, K-A, Giles, G G, Hopper, J L
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2011
主題:
Clinical Study
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065278/
https://ncbi.nlm.nih.gov/pubmed/21343941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.41
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