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Type VIII Collagen Modulates TGF-β1-induced Proliferation of Mesangial Cells

Mesangial cells in diabetic mice and human kidneys with diabetic nephropathy exhibit increased type VIII collagen, a nonfibrillar protein that exists as a heterodimer composed of α1(VIII) and α2(VIII), encoded by Col8a1 and Col8a2, respectively. Because TGF-β1 promotes the development of diabetic gl...

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Detalhes bibliográficos
Main Authors: Loeffler, Ivonne, Hopfer, Ulrike, Koczan, Dirk, Wolf, Gunter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065221/
https://ncbi.nlm.nih.gov/pubmed/21372207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010098
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