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Type VIII Collagen Modulates TGF-β1-induced Proliferation of Mesangial Cells
Mesangial cells in diabetic mice and human kidneys with diabetic nephropathy exhibit increased type VIII collagen, a nonfibrillar protein that exists as a heterodimer composed of α1(VIII) and α2(VIII), encoded by Col8a1 and Col8a2, respectively. Because TGF-β1 promotes the development of diabetic gl...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Nephrology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065221/ https://ncbi.nlm.nih.gov/pubmed/21372207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010098 |
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