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Disruption of GABAergic tone in the dorsomedial hypothalamus attenuates responses in a subset of serotonergic neurons in the dorsal raphe nucleus following lactate-induced panic

Panic patients are vulnerable to induction of panic attacks by subthreshold interoceptive stimuli such as intravenous (i.v.) sodium lactate infusions. Facilitation of serotonergic signaling with selective serotonin re-uptake inhibitors (SSRIs) can suppress anxiety and panic-like responses, but the m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Philip L., Lowry, Christopher A., Truitt, William, Shekhar, Anantha
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065198/
https://ncbi.nlm.nih.gov/pubmed/18308791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881107082900
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