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Inhaled Nitric Oxide Prevents 3-Nitrotyrosine Formation in the Lungs of Neonatal Mice Exposed to >95% Oxygen

Inhaled nitric oxide is being evaluated as a preventative therapy for patients at risk for bronchopulmonary dysplasia (BPD). Nitric oxide (NO), in the presence of superoxide, forms peroxynitrite, which reacts with tyrosine residues on proteins to form 3-nitrotyrosine (3-NT). However, NO can also act...

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Main Authors: Stenger, Michael R., Rose, Melissa J., Joshi, Mandar S., Rogers, Lynette K., Chicoine, Louis G., Bauer, John Anthony, Nelin, Leif D.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065182/
https://ncbi.nlm.nih.gov/pubmed/20237791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00408-010-9235-6
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