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Sgs1 Truncations Induce Genome Rearrangements but Suppress Detrimental Effects of BLM Overexpression in Saccharomyces cerevisiae
RecQ-like DNA helicases are conserved from bacteria to humans. They perform functions in the maintenance of genome stability, and their mutation is associated with cancer predisposition and premature aging syndromes in humans. Here, a series of C-terminal deletions and point mutations of Sgs1, the o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065180/ https://ncbi.nlm.nih.gov/pubmed/21111748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.035 |
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