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5-Aza-2′-deoxycytidine Increases Sialyl Lewis X on MUC1 by Stimulating β-Galactoside α2,3-Sialyltransferase 6 Gene

Sialyl Lewis X is a tumor-associated antigen frequently found in the advanced cancers. However, the mechanism for the production of this cancer antigen is not entirely clear. The objective of this study is to examine whether epigenetics is involved in the regulation of the formation of this antigen....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chachadi, Vishwanath B., Cheng, Helen, Klinkebiel, David, Christman, Judith K., Cheng, Pi-Wan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065031/
https://ncbi.nlm.nih.gov/pubmed/21168523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2010.12.015
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