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Antigen-Antibody docking reveals the molecular basis for cross-reactivity of the 1918 and 2009 Influenza A/H1N1 pandemic viruses

To understand the reported cross-reactivity of the 2009 H1N1 and the 1918 H1N1 pandemic viruses we docked the crystal structure of 2D1, an antibody derived from a survivor of the 1918 pandemic, to the structures of hemaglutinin (HA) of the 2009 strain and seasonal H1 vaccine strains. Our studies rev...

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Detalhes bibliográficos
Principais autores: Cherian, Sarah, hil, Pratip, Mishra, Akhilesh Chandra
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064850/
https://ncbi.nlm.nih.gov/pubmed/21464843
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