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The propeptide region of clotting factor IX is a signal for a vitamin K dependent carboxylase: evidence from protein engineering of amino acid -4.

Homologous "propeptide" regions are present in a family of vitamin K-dependent mammalian proteins, including clotting factors II, VII, IX, X, protein C, protein S and bone "gla" proteins. To test the hypothesis that the propeptide is a signal for the correct gamma-carboxylation of the adjacent gamma...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Galeffi, P, Brownlee, G G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 1987
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306484/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3684602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.22.9505
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