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Efficient, Enantioselective Assembly of Silanediol Protease Inhibitors
[Image: see text] A five-step assembly of silicon-protected dipeptide mimics from commercially available reagents is described. This methodology makes silanediol protease inhibitors readily available for the first time. The sequence features asymmetric hydrosilylation, a novel reduction of a silyl e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064730/ https://ncbi.nlm.nih.gov/pubmed/21381688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2002978 |
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