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The secondary structure of a messenger RNA precursor probed with psoralen is melted in an in vitro splicing reaction.
The secondary structure of the SP6/mouse insulin precursor RNA was determined by psoralen cross-linking experiments. A series of long-range contacts occur within the left half of the pre-mRNA that contains the intervening sequence. Multiple secondary structures for the pre-mRNA exist since some of t...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1987
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306468/ https://ncbi.nlm.nih.gov/pubmed/3317279 |
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