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miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma
Recent studies have established miR-34a as a key effector of the p53 signaling pathway and have implicated its role in multiple cancer types. Here, we establish that miR-34a induces apoptosis, G2 arrest, and senescence in medulloblastoma and renders these cells more sensitive to chemotherapeutic age...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064629/ https://ncbi.nlm.nih.gov/pubmed/21177782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq179 |
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