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Dopamine-Induced Apoptosis of Lactotropes Is Mediated by the Short Isoform of D2 Receptor

Dopamine, through D2 receptor (D2R), is the major regulator of lactotrope function in the anterior pituitary gland. Both D2R isoforms, long (D2L) and short (D2S), are expressed in lactotropes. Although both isoforms can transduce dopamine signal, they differ in the mechanism that leads to cell respo...

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Detalhes bibliográficos
Main Authors: Radl, Daniela Betiana, Ferraris, Jimena, Boti, Valeria, Seilicovich, Adriana, Sarkar, Dipak Kumar, Pisera, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064585/
https://ncbi.nlm.nih.gov/pubmed/21464994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018097
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