Severe Airway Epithelial Injury, Aberrant Repair and Bronchiolitis Obliterans Develops after Diacetyl Instillation in Rats

BACKGROUND: Bronchiolitis obliterans (BO) is a fibrotic lung disease that occurs in a variety of clinical settings, including toxin exposures, autoimmunity and lung or bone marrow transplant. Despite its increasing clinical importance, little is known regarding the underlying disease mechanisms due...

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Detalhes bibliográficos
Main Authors: Palmer, Scott M., Flake, Gordon P., Kelly, Fran L., Zhang, Helen L., Nugent, Julia L., Kirby, Patrick J., Foley, Julie F., Gwinn, William M., Morgan, Dan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064568/
https://ncbi.nlm.nih.gov/pubmed/21464978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017644
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