MEKs/ERKs inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by down regulating growth and DNA repair signals

Multimodal treatment has improved the outcome of many solid tumors, and in some cases the use of radiosensitizers has significantly contributed to this gain. Activation of the extracellular signaling kinase pathway (MEK/ERK) generally results in stimulation of cell growth and confers a survival adva...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Marampon, Francesco, Gravina, Giovanni Luca, Di Rocco, Agnese, Bonfili, Pierluigi, Di Staso, Mario, Fardella, Caterina, Polidoro, Lorella, Ciccarelli, Carmela, Festuccia, Claudio, Popov, Vladimir M., Pestell, Richard G., Tombolini, Vincenzo, Zani, Bianca Maria
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064485/
https://ncbi.nlm.nih.gov/pubmed/21220498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0631
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items