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Translocation, switching and gating: potential roles for ATP in long-range communication on DNA by Type III restriction endonucleases

To cleave DNA, the Type III RM (restriction–modification) enzymes must communicate the relative orientation of two recognition sequences, which may be separated by many thousands of base pairs. This long-range interaction requires ATP hydrolysis by a helicase domain, and both active (DNA translocati...

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Bibliografiske detaljer
Hovedforfatter: Szczelkun, Mark D.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064402/
https://ncbi.nlm.nih.gov/pubmed/21428945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0390589
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