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Translocation, switching and gating: potential roles for ATP in long-range communication on DNA by Type III restriction endonucleases
To cleave DNA, the Type III RM (restriction–modification) enzymes must communicate the relative orientation of two recognition sequences, which may be separated by many thousands of base pairs. This long-range interaction requires ATP hydrolysis by a helicase domain, and both active (DNA translocati...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064402/ https://ncbi.nlm.nih.gov/pubmed/21428945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0390589 |
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