Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

MicroRNAs (miRNAs) circulate in the bloodstream in a highly stable, extracellular form and are being developed as blood-based biomarkers for cancer and other diseases. However, the mechanism underlying their remarkable stability in the RNase-rich environment of blood is not well understood. The curr...

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Autori principali: Arroyo, Jason D., Chevillet, John R., Kroh, Evan M., Ruf, Ingrid K., Pritchard, Colin C., Gibson, Donald F., Mitchell, Patrick S., Bennett, Christopher F., Pogosova-Agadjanyan, Era L., Stirewalt, Derek L., Tait, Jonathan F., Tewari, Muneesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064324/
https://ncbi.nlm.nih.gov/pubmed/21383194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019055108
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