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PKR-dependent CHOP induction limits hyperoxia-induced lung injury
Supplemental O(2) is commonly employed in patients with respiratory failure; however, hyperoxia is also a potential contributor to lung injury. In animal models, hyperoxia causes oxidative stress in the lungs, resulting in increased inflammation, edema, and permeability. We hypothesized that oxidati...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064291/ https://ncbi.nlm.nih.gov/pubmed/21186267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00166.2010 |
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