Chronic estradiol exposure induces oxidative stress in the hypothalamus to decrease hypothalamic dopamine and cause hyperprolactinemia

Estrogens are known to cause hyperprolactinemia, most probably by acting on the tuberoinfundibular dopaminergic (TIDA) system of the hypothalamus. Dopamine (DA) produced by TIDA neurons directly inhibits prolactin secretion and, therefore, to stimulate prolactin secretion, estrogens inhibit TIDA neu...

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Main Authors: MohanKumar, Sheba M. J., Kasturi, Badrinarayanan S., Shin, Andrew C., Balasubramanian, Priya, Gilbreath, Ebony T., Subramanian, Madhan, MohanKumar, Puliyur S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064273/
https://ncbi.nlm.nih.gov/pubmed/21178126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00481.2010
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