Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF-κB Ligand (RANKL) Activation of NF-κB Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells

Resveratrol is a polyphenolic phytoestrogen that has been shown to exhibit potent anti-oxidant, anti-inflammatory, and anti-catabolic properties. Increased osteoclastic and decreased osteoblastic activities result in bone resorption and loss of bone mass. These changes have been implicated in pathol...

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Bibliografiska uppgifter
Huvudupphovsmän: Shakibaei, Mehdi, Buhrmann, Constanze, Mobasheri, Ali
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064204/
https://ncbi.nlm.nih.gov/pubmed/21239502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198713
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