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A New Autophagy-related Checkpoint in the Degradation of an ERAD-M Target
The endoplasmic reticulum (ER) harbors elaborate quality control mechanisms to ensure proper folding and post-translational modifications of polypeptides targeted to this organelle. Once an aberrant protein is detected, it is dislocated from the ER and routed to the proteasome for destruction. Autop...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064203/ https://ncbi.nlm.nih.gov/pubmed/21228276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177618 |
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