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CK2 Phosphorylation of an Acidic Ser/Thr Di-isoleucine Motif in the Na(+)/H(+) Exchanger NHE5 Isoform Promotes Association with β-Arrestin2 and Endocytosis

Internalization of the Na(+)/H(+) exchanger NHE5 into recycling endosomes is enhanced by the endocytic adaptor proteins β-arrestin1 and -2, best known for their preferential recognition of ligand-activated G protein-coupled receptors (GPCRs). However, the mechanism underlying their atypical associat...

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Detalhes bibliográficos
Main Authors: Lukashova, Viktoria, Szabó, Elöd Z., Jinadasa, Tushare, Mokhov, Alexei, Litchfield, David W., Orlowski, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064201/
https://ncbi.nlm.nih.gov/pubmed/21296876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.182881
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