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Clemastine Potentiates the Human P2X7 Receptor by Sensitizing It to Lower ATP Concentrations
P2X7 receptors have emerged as potential drug targets for the treatment of medical conditions such as e.g. rheumatoid arthritis and neuropathic pain. To assess the impact of pharmaceuticals on P2X7, we screened a compound library comprising approved or clinically tested drugs and identified several...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064161/ https://ncbi.nlm.nih.gov/pubmed/21262970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198879 |
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