TDP-43 Is a Transcriptional Repressor: THE TESTIS-SPECIFIC MOUSE acrv1 GENE IS A TDP-43 TARGET IN VIVO

TDP-43 is an evolutionarily conserved ubiquitously expressed DNA/RNA-binding protein. Although recent studies have shown its association with a variety of neurodegenerative disorders, the function of TDP-43 remains poorly understood. Here we address TDP-43 function using spermatogenesis as a model s...

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Bibliografiske detaljer
Main Authors: Lalmansingh, Avin S., Urekar, Craig J., Reddi, Prabhakara P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064152/
https://ncbi.nlm.nih.gov/pubmed/21252238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.166587
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