Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 Signaling

Fms-like tyrosine kinase 3 (FLT3) plays an important role in hematopoietic differentiation, and constitutively active FLT3 mutant proteins contribute to the development of acute myeloid leukemia. Little is known about the protein-tyrosine phosphatases (PTP) affecting the signaling activity of FLT3....

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Bibliografiska uppgifter
Huvudupphovsmän: Arora, Deepika, Stopp, Sabine, Böhmer, Sylvia-Annette, Schons, Julia, Godfrey, Rinesh, Masson, Kristina, Razumovskaya, Elena, Rönnstrand, Lars, Tänzer, Simone, Bauer, Reinhard, Böhmer, Frank-D., Müller, Jörg P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064147/
https://ncbi.nlm.nih.gov/pubmed/21262971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.205021
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