Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1–7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats

Alterations in the balance between ANG II/ACE and ANG 1–7/ACE2 in ANG II-dependent hypertension could reduce the generation of ANG 1–7 and contribute further to increased intrarenal ANG II. Upregulation of collecting duct (CD) renin may lead to increased ANG II formation during ANG II-dependent hype...

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Hlavní autoři: Prieto, Minolfa C., González-Villalobos, Romer A., Botros, Fady T., Martin, Victoria L., Pagán, Javier, Satou, Ryousuke, Lara, Lucienne S., Feng, Yumei, Fernandes, Fernanda B., Kobori, Hiroyuki, Casarini, Dulce E., Navar, L. Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064128/
https://ncbi.nlm.nih.gov/pubmed/21209009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00383.2009
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