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Role of Inflammation and Insulin Resistance in Endothelial Progenitor Cell Dysfunction

OBJECTIVE: Endothelial progenitor cells (EPCs) are decreased in number and function in type 2 diabetes. Mechanisms by which this dysfunction occurs are largely unknown. We tested the hypothesis that a chronic inflammatory environment leads to insulin signaling defects in EPCs and thereby reduces the...

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Bibliographic Details
Main Authors: Desouza, Cyrus V., Hamel, Frederick G., Bidasee, Keshore, O’Connell, Kelly
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064102/
https://ncbi.nlm.nih.gov/pubmed/21346178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0875
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