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The second STE12 homologue of Cryptococcus neoformans is MATa-specific and plays an important role in virulence

Cryptococcus neoformans STE12α, a homologue of Saccharomyces cerevisiae STE12, exists only in MATα strains. We identified another STE12 homologue, STE12a, which is MATa specific. As in the case with Δste12α, the mating efficiency for Δste12a was reduced significantly. The Δste12a strains surprisingl...

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Bibliographic Details
Main Authors: Chang, Y. C., Penoyer, L. A., Kwon-Chung, K. J.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC30641/
https://ncbi.nlm.nih.gov/pubmed/11248066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061031998
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